The phenomenon of ENSO asymmetry has been recognized for many years, but most studies have focused on the asymmetry of surface temperature anomalies in the equatorial eastern Pacific. Here, the authors investigate the temperature asymmetry associated with ENSO in the subsurface of the western Pacific through analysis of observations and numerical experiments with an ocean GCM. Both the observation and simulation exhibit significant ENSO asymmetry, characterized by negative temperature skewness in the equatorial western Pacific and positive skewness in the eastern Pacific. Heat budget analysis reveals that nonlinear dynamical heating results in the positive temperature asymmetry in the equatorial eastern Pacific, but tends to weaken the negative temperature asymmetry in the equatorial western Pacific. The climatological meridional current transports the temperature anomalies and corresponding negative asymmetry from the off-equator region to the equator in the subsurface of the western Pacific. Through a sensitivity experiment with reversed wind stress forcing, the authors suggest that the skewness of the wind stress anomalies does not contribute to the negative temperature asymmetry in the western Pacific in the first-order approximation, while the internal nonlinear dynamics does play a key role. The study suggests that, as a result of nonlinear processes, the oceanic responses to anomalous wind stress are nonlinear and asymmetric in the tropical Pacific.